RASSF5 Antibody
Product Specifications
Background
This gene is a member of the Ras association domain family. It functions as a tumor suppressor, and is inactivated in a variety of cancers. The encoded protein localizes to centrosomes and microtubules, and associates with the GTP-activated forms of Ras, Rap1, and several other Ras-like small GTPases. The protein regulates lymphocyte adhesion and suppresses cell growth in response to activated Rap1 or Ras. Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
83593
Swiss Prot
Q8WWW0
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-265 of human RASSF5 (NP_872606.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cancer, Cell Cycle, Immunology, Signal Transduction
Purification
Affinity purification
Positive Control
THP-1
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 37kDa, 45kDa
Fragment
IgG
Symbol
RASSF5
Positive Control 2
A-549
Positive Control 3
293T
Positive Control 4
Jurkat
Positive Control 5
Mouse brain
Positive Control 6
Mouse liver
NCBI Official Name
Ras association (RalGDS/AF-6) domain family member 5
NCBI Organism
Homo sapiens
Other Product Names
NORE1, RAPL, Ras association domain-containing protein 5, New ras effector 1, Maxp1, NORE1A, NORE1B, RASSF3
Tested Applications
WB, IHC
Physical Properties
Liquid
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