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PPAN Antibody

Product Specifications

Background

The protein encoded by this gene is an evolutionarily conserved protein similar to yeast SSF1 as well as to the gene product of the Drosophila gene peter pan (ppan) . SSF1 is known to be involved in the second step of mRNA splicing. Both SSF1 and ppan are essential for cell growth and proliferation. Exogenous expression of this gene was reported to reduce the anchorage-independent growth of some tumor cells. Read-through transcription of this gene with P2RY11/P2Y (11), an adjacent downstream gene that encodes an ATP receptor, has been found. These read-through transcripts are ubiquitously present and up-regulated during granulocyte differentiation.

NCBI Gene ID

56342

Swiss Prot

Q9NQ55

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PPAN (NP_064615.3) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

Affinity purification

Positive Control

U-87MG

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=22-900

Calculated Molecular Weight

Observed: 53kDa/55kDa

Fragment

IgG

Symbol

PPAN

Positive Control 2

Mouse heart

NCBI Official Name

Suppressor of SWI4 1 homolog

NCBI Organism

Homo sapiens

Other Product Names

Suppressor of SWI4 1 homolog, Ssf-1, Brix domain-containing protein 3, Peter Pan homolog, PPAN, BXDC3, SSF1

Tested Applications

WB, IHC, IF

Physical Properties

Liquid

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