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PON1 Antibody

Product Specifications

Background

The enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21.3.

NCBI Gene ID

5444

Swiss Prot

P27169

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 20-150 of human PON1 (NP_000437.3) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Neuroscience, Signal Transduction

Purification

Affinity purification

Positive Control

293T

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 40kDa/55kDa

Fragment

IgG

Symbol

PON1

Positive Control 2

Jurkat

Positive Control 3

Mouse thymus

Positive Control 4

Mouse heart

Positive Control 5

Rat liver

NCBI Official Name

Paraoxonase 1

NCBI Organism

Homo sapiens

Other Product Names

PON1, ESA, PON, MVCD5

Tested Applications

WB, IHC

Physical Properties

Liquid

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