PAX6 Antibody
Product Specifications
Background
This gene encodes a homeobox and paired domain-containing protein that binds DNA and functions as a regulator of transcription. Activity of this protein is key in the development of neural tissues, particularly the eye. This gene is regulated by multiple enhancers located up to hundreds of kilobases distant from this locus. Mutations in this gene or in the enhancer regions can cause ocular disorders such as aniridia and Peter's anomaly. Use of alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms.
NCBI Gene ID
5080
Swiss Prot
P26367
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PAX6 (NP_000271.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Neuroscience, Signal Transduction, Stem Cell, Transcription
Purification
Affinity purification
Positive Control
SW480
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 47kDa
Fragment
IgG
Symbol
PAX6
Positive Control 2
22Rv1
Positive Control 3
NCI-H460
Positive Control 4
HepG2
Positive Control 5
Mouse brain
Positive Control 6
Mouse eye
NCBI Official Name
Paired box 6
NCBI Organism
Homo sapiens
Other Product Names
PAX6, AN, AN2, D11S812E, MGC17209, MGDA, WAGR
Tested Applications
WB, IF
Physical Properties
Liquid
Curated Selection
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