KU70 Antibody
Product Specifications
Background
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V (D) J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
NCBI Gene ID
2547
Swiss Prot
P12956
Host
Rabbit
Reactivity
Human, Mouse, Rat, Monkey
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 408-609 of human KU70 (NP_001460.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle
Purification
Affinity purification
Positive Control
COS-7
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 70kDa
Fragment
IgG
Symbol
XRCC6
Positive Control 2
SW480
Positive Control 3
Mouse brain
NCBI Official Name
X-ray repair complementing defective repair in Chinese hamster cells 6
NCBI Organism
Homo sapiens
Other Product Names
G22P1, ML8, KU70, TLAA, CTC75, CTCBF, G22P1
Tested Applications
WB, IHC, IF, IP
Physical Properties
Liquid
Curated Selection
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