NFYB Antibody
Product Specifications
Background
The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence; protein sequence alignments and experiments with mutants.
NCBI Gene ID
4801
Swiss Prot
P25208
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-207 of human NFYB (NP_006157.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction, Transcription
Purification
Affinity purification
Positive Control
HL-60
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 28-30kDa
Fragment
IgG
Symbol
NFYB
Positive Control 2
SKOV3
Positive Control 3
HeLa
Positive Control 4
Mouse liver
Positive Control 5
Mouse spleen
Positive Control 6
Mouse brain
NCBI Official Name
Nuclear transcription factor Y, beta
NCBI Organism
Homo sapiens
Other Product Names
NFYB, HAP3, CBF-A, CBF-B, NF-YB
Tested Applications
WB, IF
Physical Properties
Liquid
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