Acetyl-Histone H3-K18 pAb
Product Specifications
Background
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.
NCBI Gene ID
8356
Swiss Prot
P68431
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
A synthetic acetylated peptide corresponding to residues surrounding K18 of human H3
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
BT-474
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
Acetylated
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=22-816
Calculated Molecular Weight
Observed: 16kDa
Fragment
IgG
Symbol
H3K18ac
Positive Control 2
293T
Positive Control 3
H3
NCBI Official Name
Histone cluster 1, H3d
NCBI Organism
Homo sapiens
Other Product Names
H3/b, H3FB, ERBB, ERBB1, HER1, H3/a, H3/c, H3/d, H3/f, H3/h
Tested Applications
WB, IHC, IF, IP, ChIP, ChIPseq
Physical Properties
Liquid
Curated Selection
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