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Alpha smooth muscle actin Antibody

Product Specifications

Background

The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified.

NCBI Gene ID

59

Swiss Prot

P62736

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-377 of human alpha smooth muscle actin (NP_001135417.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Neuroscience, Signal Transduction, Stem Cell

Purification

Affinity purification

Positive Control

SW480

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 42kDa

Fragment

IgG

Symbol

ACTA2

Positive Control 2

MCF7

Positive Control 3

HeLa

Positive Control 4

HepG2

Positive Control 5

Mouse heart

Positive Control 6

Mouse testis

NCBI Official Name

Actin, alpha 2, smooth muscle, aorta

NCBI Organism

Homo sapiens

Other Product Names

ACTA2, ACTSA, actin, alpha 2, smooth muscle, aorta, alpha-cardiac actin, ACTVS, GIG46

Tested Applications

WB, IF

Physical Properties

Liquid

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