POLD3 Antibody
Product Specifications
Background
This gene encodes the 66-kDa subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein plays a role in regulating the activity of DNA polymerase delta through interactions with other subunits and the processivity cofactor proliferating cell nuclear antigen (PCNA) . Alternatively spliced transcript variants have been observed for this gene.
NCBI Gene ID
10714
Swiss Prot
Q15054
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 197-466 of human POLD3 (NP_006582.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
THP-1
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 51kDa
Fragment
IgG
Symbol
POLD3
Positive Control 2
HepG2
Positive Control 3
HeLa
Positive Control 4
MCF7
Positive Control 5
H460
Positive Control 6
Mouse brain
NCBI Official Name
DNA polymerase delta subunit 3
NCBI Organism
Homo sapiens
Other Product Names
DNA polymerase delta subunit 3, DNA polymerase delta subunit p66, POLD3, KIAA0039
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
Curated Selection
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