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IL22RA2 Antibody

Product Specifications

Background

This gene encodes a member of the class II cytokine receptor family. The encoded soluble protein specifically binds to and inhibits interleukin 22 activity by blocking the interaction of interleukin 22 with its cell surface receptor. The encoded protein may be important in the regulation of inflammatory response, and has been implicated in the regulation of tumorigenesis in the colon. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

NCBI Gene ID

116379

Swiss Prot

Q969J5

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 22-231 of human IL22RA2 (NP_851826.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Chemokines & Cytokines, Immunology, Innate Immunity

Purification

Affinity purification

Positive Control

Mouse spleen

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 31kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

IL22RA2

Positive Control 2

Mouse lung

Positive Control 3

Rat spleen

Positive Control 4

Rat brain

Positive Control 5

Rat liver

NCBI Official Name

Interleukin-22 receptor subunit alpha-2

NCBI Organism

Homo sapiens

Other Product Names

Interleukin-22 receptor subunit alpha-2, IL-22 receptor subunit alpha-2, IL-22R-alpha-2, IL-22RA2, Cytokine receptor class-II member 10, Cytokine receptor family 2 member 10, CRF2-10, Cytokine receptor family type 2, soluble 1, CRF2-S1, Interleukin-22-binding protein, IL-22BP, IL22BP, ZcytoR16, IL22RA2

Tested Applications

WB

Physical Properties

Liquid

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