SOX6 Antibody
Product Specifications
Background
This gene encodes a member of the D subfamily of sex determining region y-related transcription factors that are characterized by a conserved DNA-binding domain termed the high mobility group box and by their ability to bind the minor groove of DNA. The encoded protein is a transcriptional activator that is required for normal development of the central nervous system, chondrogenesis and maintenance of cardiac and skeletal muscle cells. The encoded protein interacts with other family members to cooperatively activate gene expression. Alternative splicing results in multiple transcript variants.
NCBI Gene ID
55553
Swiss Prot
P35712
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-74 of human SOX6 (NP_001139291.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction, Transcription
Purification
Affinity purification
Positive Control
U-87MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 110kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
SOX6
Positive Control 2
HT-29
Positive Control 3
Jurkat
Positive Control 4
Mouse kidney
Positive Control 5
Mouse skeletal muscle
Positive Control 6
Rat kidney
NCBI Official Name
SRY-box transcription factor 6
NCBI Organism
Homo sapiens
Other Product Names
HSSOX6, SOXD, transcription factor SOX-6, SRY (sex determining region Y) -box 6, SRY-box 6, SRY-box containing gene 6
Tested Applications
WB
Physical Properties
Liquid
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