NFU1 Antibody

Product Specifications

Background

This gene encodes a protein that is localized to mitochondria and plays a critical role in iron-sulfur cluster biogenesis. The encoded protein assembles and transfers 4Fe-4S clusters to target apoproteins including succinate dehydrogenase and lipoic acid synthase. Mutations in this gene are a cause of multiple mitochondrial dysfunctions syndrome-1, and pseudogenes of this gene are located on the short arms of chromosomes 1 and 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

NCBI Gene ID

27247

Swiss Prot

Q9UMS0

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human NFU1 (NP_001002755.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Affinity purification

Positive Control

BT-474

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 25-28kDa

Fragment

IgG

Symbol

NFU1

Positive Control 2

SW480

Positive Control 3

THP-1

Positive Control 4

U-937

Positive Control 5

Mouse liver

Positive Control 6

Mouse heart

NCBI Official Name

NFU1 iron-sulfur cluster scaffold

NCBI Organism

Homo sapiens

Other Product Names

CGI-33, HIRIP, HIRIP5, MMDS1, NIFUC, Nfu, NifU, NFU1 iron-sulfur cluster scaffold homolog, mitochondrial, HIRA-interacting protein 5, NifU-like C-terminal domain containing, iron-sulfur cluster scaffold protein