VPS4A Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. The mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be really an yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 16; the gene for the other resides on chromosome 18.
NCBI Gene ID
27183
Swiss Prot
Q9UN37
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human VPS4A (NP_037377.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Chemokines & Cytokines, Immunology, Signal Transduction
Purification
Affinity purification
Positive Control
MCF7
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 49kDa
Fragment
IgG
Symbol
VPS4A
Positive Control 2
HeLa
Positive Control 3
U-87MG
Positive Control 4
SW620
Positive Control 5
A673
Positive Control 6
Mouse brain
NCBI Official Name
Vacuolar protein sorting 4 homolog A (S. cerevisiae)
NCBI Organism
Homo sapiens
Other Product Names
VPS4A, FLJ22197, SKD1, SKD2, VPS4, VPS4-1, SKD1A
Tested Applications
WB, IHC
Physical Properties
Liquid
Frequently Asked Questions
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