NSL1 Antibody

Product Specifications

Background

This gene encodes a protein with two coiled-coil domains that localizes to kinetochores, which are chromosome-associated structures that attach to microtubules and mediate chromosome movements during cell division. The encoded protein is part of a conserved protein complex that includes two chromodomain-containing proteins and a component of the outer plate of the kinetochore. This protein complex is proposed to bridge centromeric heterochromatin with the outer kinetochore structure. Multiple transcript variants encoding different isoforms have been found for this gene. There is a pseudogene of the 3' UTR region of this gene on chromosome X.

NCBI Gene ID

25936

Swiss Prot

Q96IY1

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-281 of human NSL1 (NP_056286.3) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

Affinity purification

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Fragment

IgG

Symbol

NSL1

NCBI Official Name

NSL1 component of MIS12 kinetochore complex

NCBI Organism

Homo sapiens

Other Product Names

C1orf48, DC8, MIS14, kinetochore-associated protein NSL1 homolog, NSL1, MIND kinetochore complex component, homolog, NSL1, MIS12 kinetochore complex component