FASTK Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined.
NCBI Gene ID
10922
Swiss Prot
Q14296
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 360-549 of human FASTK (NP_006703.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
NCI-H460
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 61kDa
Fragment
IgG
Symbol
FASTK
Positive Control 2
Mouse brain
NCBI Official Name
Fas-activated serine/threonine kinase
NCBI Organism
Homo sapiens
Other Product Names
Fas-activated serine/threonine kinase, FAST kinase, FASTK
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
Curated Selection
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