ALDH1L1 Antibody
Product Specifications
Background
The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants.
NCBI Gene ID
10840
Swiss Prot
O75891
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human ALDH1L1 (NP_036322.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cancer, Cell Cycle, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
HepG2
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 120kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
ALDH1L1
Positive Control 2
MCF7
Positive Control 3
Jurkat
Positive Control 4
Mouse liver
Positive Control 5
Mouse brain
Positive Control 6
Mouse heart
NCBI Official Name
Aldehyde dehydrogenase 1 family, member L1
NCBI Organism
Homo sapiens
Other Product Names
ALDH1L1, DKFZp781N0997, FTHFD, FDH, 10-fTHF, 10-FTHFDH
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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