PDIA6 Antibody
Product Specifications
Background
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, two catalytically active thioredoxin (TRX) domains, a TRX-like domain, and a C-terminal ER-retention sequence. This protein inhibits the aggregation of misfolded proteins and exhibits both isomerase and chaperone activity. Alternative splicing results in multiple transcript variants encoding different isoforms.
NCBI Gene ID
10130
Swiss Prot
Q15084
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of human PDIA6 (NP_005733.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Affinity purification
Positive Control
HL-60
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 48kDa
Fragment
IgG
Symbol
PDIA6
Positive Control 2
SW480
Positive Control 3
HepG2
Positive Control 4
THP-1
Positive Control 5
Mouse liver
Positive Control 6
Mouse lung
NCBI Official Name
Protein disulfide isomerase family A, member 6
NCBI Organism
Homo sapiens
Other Product Names
PDIA6, ERP5, P5, TXNDC7
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
Curated Selection
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