NCOR1 Antibody
Product Specifications
Background
This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.
NCBI Gene ID
9611
Swiss Prot
O75376
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human NCOR1 (NP_006302.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
22Rv1
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 320kDa
Fragment
IgG
Symbol
NCOR1
Positive Control 2
HeLa
Positive Control 3
HepG2
Positive Control 4
Jurkat
NCBI Official Name
Nuclear receptor corepressor 1
NCBI Organism
Homo sapiens
Other Product Names
NCOR1, N-CoR, TRAC1, N-CoR1, hN-CoR
Tested Applications
WB, IF
Physical Properties
Liquid
Curated Selection
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