DNAJA3 Antibody
Product Specifications
Background
This gene encodes a member of the DNAJ/Hsp40 protein family. DNAJ/Hsp40 proteins stimulate the ATPase activity of Hsp70 chaperones and play critical roles in protein folding, degradation, and multimeric complex assembly. The encoded protein is localized to mitochondria and mediates several cellular processes including proliferation, survival and apoptotic signal transduction. The encoded protein also plays a critical role in tumor suppression through interactions with oncogenic proteins including ErbB2 and the p53 tumor suppressor protein. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
NCBI Gene ID
9093
Swiss Prot
Q96EY1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 221-480 of human DNAJA3 (NP_005138.3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
BT-474
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 52kDa
Fragment
IgG
Symbol
DNAJA3
Positive Control 2
Jurkat
Positive Control 3
293T
Positive Control 4
HepG2
Positive Control 5
Mouse liver
Positive Control 6
Mouse kidney
NCBI Official Name
DnaJ (Hsp40) homolog, subfamily A, member 3
NCBI Organism
Homo sapiens
Other Product Names
DNAJA3, DnaJ protein Tid-1, HTID-1, HCA57, TID1
Tested Applications
WB, IHC
Physical Properties
Liquid
Curated Selection
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