AP3B1 Antibody

Product Specifications

Background

This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. The encoded protein is part of the heterotetrameric AP-3 protein complex which interacts with the scaffolding protein clathrin. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 2. Two transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

8546

Swiss Prot

O00203

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 895-1094 of human AP3B1 (NP_003655.3) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

Affinity purification

Positive Control

SKOV3

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 132kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

AP3B1

Positive Control 2

SW620

Positive Control 3

Mouse liver

NCBI Official Name

Adaptor related protein complex 3 subunit beta 1

NCBI Organism

Homo sapiens

Other Product Names

ADTB3, ADTB3A, HPS, HPS2, PE, AP-3 complex subunit beta-1, AP-3 complex beta-3A subunit, adaptor protein complex AP-3 subunit beta-1, adaptor related protein complex 3 beta 1 subunit, beta-3A-adaptin, clathrin assembly protein complex 3 beta-1 large chain