HIRIP3 Antibody
Product Specifications
Background
The HIRA protein shares sequence similarity with Hir1p and Hir2p, the two corepressors of histone gene transcription characterized in the yeast, Saccharomyces cerevisiae. The structural features of the HIRA protein suggest that it may function as part of a multiprotein complex. Several cDNAs encoding HIRA-interacting proteins, or HIRIPs, have been identified. In vitro, the protein encoded by this gene binds HIRA, as well as H2B and H3 core histones, indicating that a complex containing HIRA-HIRIP3 could function in some aspects of chromatin and histone metabolism. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
NCBI Gene ID
8479
Swiss Prot
Q9BW71
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 417-556 of human HIRIP3 (NP_003600.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Stem Cell
Purification
Affinity purification
Positive Control
HL-60
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 62kDa
Fragment
IgG
Symbol
HIRIP3
Positive Control 2
HeLa
Positive Control 3
U-937
Positive Control 4
Jurkat
Positive Control 5
Mouse skeletal muscle
Positive Control 6
Mouse liver
NCBI Official Name
HIRA-interacting protein 3
NCBI Organism
Homo sapiens
Other Product Names
HIRA-interacting protein 3, HIRIP3
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
Curated Selection
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