TCEB3 Antibody
Product Specifications
Background
This gene encodes the protein elongin A, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.
NCBI Gene ID
6924
Swiss Prot
Q14241
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 679-798 of human TCEB3 (NP_003189.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
BT-474
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=22-616
Calculated Molecular Weight
Observed: 105kDa
Fragment
IgG
Symbol
TCEB3
Positive Control 2
HeLa
Positive Control 3
Raji
Positive Control 4
Mouse testis
NCBI Official Name
Transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
NCBI Organism
Homo sapiens
Other Product Names
TCEB3, EloA, SIII, TCEB3A, SIII p110
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
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