STK3 Antibody
Product Specifications
Background
This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C-terminal portion. The N-terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
6788
Swiss Prot
Q13188
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 323-450 of human STK3 (NP_006272.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Autophagy, Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
293T
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 65kDa, 37kDa
Fragment
IgG
Symbol
STK3
Positive Control 2
HeLa
Positive Control 3
Jurkat
Positive Control 4
MCF7
Positive Control 5
NIH/3T3
Positive Control 6
Mouse liver
NCBI Official Name
Serine/threonine kinase 3
NCBI Organism
Homo sapiens
Other Product Names
STK3, FLJ90748, KRS1, MST2
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
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