RAD51B Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata.

NCBI Gene ID

5890

Swiss Prot

O15315

Host

Rabbit

Reactivity

Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-384 of human RAD51B (NP_598193.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Affinity purification

Positive Control

Mouse kidney

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 42kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

RAD51B

Positive Control 2

Rat kidney

NCBI Official Name

RAD51 paralog B

NCBI Organism

Homo sapiens

Other Product Names

RAD51L1, RAD51-like 1 (S. cerevisiae), REC2, HREC2, R51H2, RAD51B, RAD51 homolog B, RecA-like protein, recombination repair protein, DNA repair protein RAD51 homolog 2, RAD51L1