RAD51C Antibody
Product Specifications
Background
This gene is a member of the RAD51 family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51 and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with other RAD51 paralogs and is reported to be important for Holliday junction resolution. Mutations in this gene are associated with Fanconi anemia-like syndrome. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing results in multiple transcript variants.
NCBI Gene ID
5889
Swiss Prot
O43502
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-135 of human RAD51C (NP_002867.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
MCF7
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 42kDa
Fragment
IgG
Symbol
RAD51C
Positive Control 2
SW480
Positive Control 3
BT-474
NCBI Official Name
RAD51 paralog C
NCBI Organism
Homo sapiens
Other Product Names
RAD51C, RAD51 homolog C (S. cerevisiae), RAD51L2, yeast RAD51 homolog 3, DNA repair protein RAD51 homolog 3
Tested Applications
WB, IHC
Physical Properties
Liquid
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