OPHN1 Antibody
Product Specifications
Background
This gene encodes a Rho-GTPase-activating protein that promotes GTP hydrolysis of Rho subfamily members. Rho proteins are important mediators of intracellular signal transduction, which affects cell migration and cell morphogenesis. Mutations in this gene are responsible for OPHN1-related X-linked mental retardation with cerebellar hypoplasia and distinctive facial dysmorhphism.
NCBI Gene ID
4983
Swiss Prot
O60890
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human OPHN1 (NP_002538.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
HepG2
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 92kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
OPHN1
Positive Control 2
Mouse spleen
NCBI Official Name
Oligophrenin 1
NCBI Organism
Homo sapiens
Other Product Names
ARHGAP41, MRX6OPN1, oligophrenin-1, mental retardation, X-linked 6oligophrenin-1, Rho-GTPase activating protein
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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