LGALS3BP Antibody
Product Specifications
Background
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV) . It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1.
NCBI Gene ID
3959
Swiss Prot
Q08380
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 306-585 of human LGALS3BP (NP_005558.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle
Purification
Affinity purification
Positive Control
HepG2
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 75kDa-110kDa
Fragment
IgG
Symbol
LGALS3BP
Positive Control 2
HT-29
Positive Control 3
293T
Positive Control 4
HeLa
Positive Control 5
Mouse liver
Positive Control 6
Mouse kidney
NCBI Official Name
Lectin, galactoside-binding, soluble, 3 binding protein
NCBI Organism
Homo sapiens
Other Product Names
LGALS3BP, 90K, MAC-2-BP, BTBD17B, TANGO10B
Tested Applications
WB, IF
Physical Properties
Liquid
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