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KLRB1 Antibody

Product Specifications

Background

Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain. The KLRB1 protein is classified as a type II membrane protein because it has an external C terminus.

NCBI Gene ID

3820

Swiss Prot

Q12918

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 73-140 of human KLRB1 (NP_002249.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Purification

Affinity purification

Positive Control

Rat liver

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 47kDa

Fragment

IgG

Symbol

KLRB1

Positive Control 2

HT-29

Positive Control 3

Mouse liver

NCBI Official Name

Killer cell lectin-like receptor subfamily B, member 1

NCBI Organism

Homo sapiens

Other Product Names

CLEC5B, NKRP1A, Killer cell lectin-like receptor subfamily B member 1, C-type lectin domain family 5 member B, NKR-P1A, NKR, CD161, NKR-P1, hNKR-P1A

Tested Applications

WB, IHC, IF

Physical Properties

Liquid

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