FKBP3 Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.
NCBI Gene ID
2287
Swiss Prot
Q00688
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-224 of human FKBP3 (NP_002004.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
HeLa
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 30kDa
Fragment
IgG
Symbol
FKBP3
Positive Control 2
MCF-7
Positive Control 3
BT-474
NCBI Official Name
FK506 binding protein 3, 25kDa
NCBI Organism
Homo sapiens
Other Product Names
FKBP3, 25 kDa FK506-binding protein, 25 kDa FKBP, FKBP-3, Immunophilin FKBP25, FK506-binding protein 3, FK506-binding protein 3 (25kD), PPIase FKBP3, Rapamycin binding protein, Rotamase, PPIase, FK506 binding protein 3, 25kDa, FKBP-25, FKBP25
Tested Applications
WB, IF, IP
Physical Properties
Liquid
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