DGKA Antibody
Product Specifications
Background
The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It acts as a modulator that competes with protein kinase C for the second messenger diacylglycerol in intracellular signaling pathways. It also plays an important role in the resynthesis of phosphatidylinositols and phosphorylating diacylglycerol to phosphatidic acid. Several transcript variants encoding different isoforms have been identified for this gene.
NCBI Gene ID
1606
Swiss Prot
P23743
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human DGKA (NP_958852.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Affinity purification
Positive Control
NCI-H460
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 83kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
DGKA
Positive Control 2
MCF7
Positive Control 3
HeLa
Positive Control 4
Mouse spleen
Positive Control 5
Mouse lung
Positive Control 6
Rat lung
NCBI Official Name
Diacylglycerol kinase alpha
NCBI Organism
Homo sapiens
Other Product Names
Diacylglycerol kinase alpha, DAG kinase alpha, 80 kDa diacylglycerol kinase, Diglyceride kinase alpha, DGK-alpha, DGKA, DAGK, DAGK1
Tested Applications
WB
Physical Properties
Liquid
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