ATOX1 Antibody
Product Specifications
Background
This gene encodes a copper chaperone that plays a role in copper homeostasis by binding and transporting cytosolic copper to ATPase proteins in the trans-Golgi network for later incorporation to the ceruloplasmin. This protein also functions as an antioxidant against superoxide and hydrogen peroxide, and therefore, may play a significant role in cancer carcinogenesis. Because of its cytogenetic location, this gene represents a candidate gene for 5q-syndrome.
NCBI Gene ID
475
Swiss Prot
O00244
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-68 of human ATOX1 (NP_004036.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
SW480
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 12kDa
Fragment
IgG
Symbol
ATOX1
Positive Control 2
K-562
NCBI Official Name
Antioxidant 1 copper chaperone
NCBI Organism
Homo sapiens
Other Product Names
ATX1, HAH1, copper transport protein ATOX1, ATX1 antioxidant protein 1 homolog, metal transport protein ATX1
Tested Applications
WB, IF
Physical Properties
Liquid
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