APLP1 Antibody
Product Specifications
Background
This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described.
NCBI Gene ID
333
Swiss Prot
P51693
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 39-300 of human APLP1 (NP_005157.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cell Cycle, Neuroscience
Purification
Affinity purification
Positive Control
A-549
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 68kDa
Fragment
IgG
Symbol
APLP1
Positive Control 2
HeLa
Positive Control 3
SH-SY5Y
Positive Control 4
Mouse brain
Positive Control 5
Mouse stomach
Positive Control 6
Mouse kidney
NCBI Official Name
Amyloid beta precursor like protein 1
NCBI Organism
Homo sapiens
Other Product Names
APLP, amyloid-like protein 1, amyloid beta (A4) precursor-like protein 1, amyloid precursor-like protein 1
Tested Applications
WB, IF
Physical Properties
Liquid
Curated Selection
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