NUDT2 Antibody
Product Specifications
Background
This gene encodes a member of the MutT family of nucleotide pyrophosphatases, a subset of the larger NUDIX hydrolase family. The gene product possesses a modification of the MutT sequence motif found in certain nucleotide pyrophosphatases. The enzyme asymmetrically hydrolyzes Ap4A to yield AMP and ATP and is responsible for maintaining the intracellular level of the dinucleotide Ap4A, the function of which has yet to be established. This gene may be a candidate tumor suppressor gene. Alternative splicing has been observed at this locus and four transcript variants, all encoding the same protein, have been identified.
NCBI Gene ID
318
Swiss Prot
P50583
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-147 of human NUDT2 (NP_001152.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cell Cycle
Purification
Affinity purification
Positive Control
SKOV3
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=22-516
Calculated Molecular Weight
Observed: 17kDa
Fragment
IgG
Symbol
NUDT2
Positive Control 2
HL-60
Positive Control 3
Mouse kidney
Positive Control 4
Mouse heart
Positive Control 5
Mouse brain
Positive Control 6
Mouse liver
NCBI Official Name
Bis (5'-nucleosyl) -tetraphosphatase [asymmetrical]
NCBI Organism
Homo sapiens
Other Product Names
Bis (5'-nucleosyl) -tetraphosphatase [asymmetrical], Diadenosine 5',5'''-P1, P4-tetraphosphate asymmetrical hydrolase, Ap4A hydrolase, Ap4Aase, Diadenosine tetraphosphatase, Nucleoside diphosphate-linked moiety X motif 2, Nudix motif 2, NUDT2, APAH1
Tested Applications
WB, IF
Physical Properties
Liquid
Curated Selection
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