USP1 Antibody
Product Specifications
Background
This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. The protein specifically deubiquitinates a protein in the Fanconi anemia (FA) DNA repair pathway. Alternate transcriptional splice variants have been characterized.
NCBI Gene ID
7398
Swiss Prot
O94782
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 486-785 of human USP1 (NP_003359.3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
Affinity purification
Positive Control
293T
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 115kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
USP1
Positive Control 2
HepG2
Positive Control 3
MCF7
Positive Control 4
Mouse testis
Positive Control 5
Mouse spleen
Positive Control 6
Mouse brain
NCBI Official Name
Ubiquitin carboxyl-terminal hydrolase 1
NCBI Organism
Homo sapiens
Other Product Names
Ubiquitin carboxyl-terminal hydrolase 1, Deubiquitinating enzyme 1, hUBP, Ubiquitin thioesterase 1, Ubiquitin-specific-processing protease 1, USP1
Tested Applications
WB
Physical Properties
Liquid
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