SURF1 Antibody
Product Specifications
Background
This gene encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency.
NCBI Gene ID
6834
Swiss Prot
Q15526
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 80-275 of human SURF1 (NP_003163.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Affinity purification
Positive Control
SW480
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 33kDa
Fragment
IgG
Symbol
SURF1
Positive Control 2
HL-60
Positive Control 3
BT-474
Positive Control 4
SKOV3
Positive Control 5
U-251MG
Positive Control 6
Mouse liver
NCBI Official Name
SURF1 cytochrome c oxidase assembly factor
NCBI Organism
Homo sapiens
Other Product Names
CMT4K, surfeit locus protein 1, surfeit 1
Tested Applications
WB, IHC
Physical Properties
Liquid
Curated Selection
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