SPINT2 Antibody
Product Specifications
Background
This gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. This gene is a putative tumor suppressor, and mutations in this gene result in congenital sodium diarrhea. Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
10653
Swiss Prot
O43291
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 28-197 of human SPINT2 (NP_066925.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Neuroscience
Purification
Affinity purification
Positive Control
MCF7
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 34kDa
Fragment
IgG
Symbol
SPINT2
NCBI Official Name
Serine peptidase inhibitor, Kunitz type, 2
NCBI Organism
Homo sapiens
Other Product Names
SPINT2, HAI-2, HAI2, Kop, PB, DIAR3
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
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