SMPD1 / ASM Antibody
Product Specifications
Background
The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB) . Multiple transcript variants encoding different isoforms have been identified.
NCBI Gene ID
6609
Swiss Prot
P17405
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 70-340 of human SMPD1 / ASM (NP_000534.3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cancer, Cell Cycle, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
Mouse kidney
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 60kDa
Fragment
IgG
Symbol
SMPD1
Positive Control 2
Mouse heart
Positive Control 3
Mouse lung
Positive Control 4
Rat liver
NCBI Official Name
Sphingomyelin phosphodiesterase 1, acid lysosomal
NCBI Organism
Homo sapiens
Other Product Names
SMPD1, ASM, NPD, ASMASE
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
Curated Selection
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