RAMP3 Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs) . RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP3) protein, CRLR functions as an adrenomedullin receptor.
NCBI Gene ID
10268
Swiss Prot
O60896
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-118 of human RAMP3 (NP_005847.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Growth Factors, Signal Transduction
Purification
Affinity purification
Positive Control
MCF7
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=22-431
Calculated Molecular Weight
Observed: 40kDa
Fragment
IgG
Symbol
RAMP3
Positive Control 2
SW620
Positive Control 3
Mouse brain
Positive Control 4
Mouse skin
Positive Control 5
Mouse kidney
Positive Control 6
Mouse heart
NCBI Official Name
Receptor (G protein-coupled) activity modifying protein 3
NCBI Organism
Homo sapiens
Other Product Names
RAMP3
Tested Applications
WB, IF
Physical Properties
Liquid
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