PUF60 Antibody
Product Specifications
Background
This gene encodes a nucleic acid-binding protein that plays a role in a variety of nuclear processes, including pre-mRNA splicing and transcriptional regulation. The encoded protein forms a complex with the far upstream DNA element (FUSE) and FUSE-binding protein at the myelocytomatosis oncogene (MYC) promoter. This complex represses MYC transcription through the core-TFIIH basal transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
NCBI Gene ID
22827
Swiss Prot
Q9UHX1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 243-542 of human PUF60 (NP_055096.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cell Cycle, Transcription
Purification
Affinity purification
Positive Control
THP-1
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 65kDa
Fragment
IgG
Symbol
PUF60
Positive Control 2
A-549
Positive Control 3
Mouse brain
Positive Control 4
Mouse thymus
Positive Control 5
Mouse spleen
Positive Control 6
Rat lung
NCBI Official Name
Poly-U binding splicing factor 60KDa
NCBI Organism
Homo sapiens
Other Product Names
PUF60, FIR, FLJ31379, RoBPI, SIAHBP1, VRJS
Tested Applications
WB, IHC, IF, IP
Physical Properties
Liquid
Curated Selection
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