PPP1R8 Antibody
Product Specifications
Background
This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.
NCBI Gene ID
5511
Swiss Prot
Q12972
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-209 of human PPP1R8 (NP_612568.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
HL-60
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 40kDa
Fragment
IgG
Symbol
PPP1R8
Positive Control 2
PC-12
Positive Control 3
HeLa
Positive Control 4
HepG2
Positive Control 5
293T
Positive Control 6
Mouse brain
NCBI Official Name
Protein phosphatase 1, regulatory subunit 8
NCBI Organism
Homo sapiens
Other Product Names
PPP1R8, ARD-1, ARD1, NIPP-1, NIPP1, PRO2047
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
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