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PPAT Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the purine/pyrimidine phosphoribosyltransferase family. It is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosythetic pathway. This gene and PAICS/AIRC gene, a bifunctional enzyme catalyzing steps six and seven of this pathway, are located in close proximity on chromosome 4, and divergently transcribed from an intergenic region.

NCBI Gene ID

5471

Swiss Prot

Q06203

Host

Rabbit

Reactivity

Human, Mouse, Rat, Monkey

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human PPAT (NP_002694.3) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

Affinity purification

Positive Control

HepG2

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=22-415

Calculated Molecular Weight

Observed: 55kDa

Fragment

IgG

Symbol

PPAT

Positive Control 2

COS-7

NCBI Official Name

Phosphoribosyl pyrophosphate amidotransferase

NCBI Organism

Homo sapiens

Other Product Names

PPAT, ATASE, GPAT, PRAT

Tested Applications

WB, IF

Physical Properties

Liquid

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