PNKP Antibody
Product Specifications
Background
This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.
NCBI Gene ID
11284
Swiss Prot
Q96T60
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 60-320 of human PNKP (NP_009185.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
HL-60
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 57kDa
Fragment
IgG
Symbol
PNKP
Positive Control 2
HepG2
Positive Control 3
Rat liver
NCBI Official Name
Polynucleotide kinase 3'-phosphatase
NCBI Organism
Homo sapiens
Other Product Names
PNKP, polynucleotide kinase 3'-phosphatase, PNK, polynucleotide kinase 3-prime-phosphatase, MCSZ, EIEE10
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
Curated Selection
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