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PDCD6 Antibody

Product Specifications

Background

This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is also located on the short arm of chromosome 5.

NCBI Gene ID

10016

Swiss Prot

O75340

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-191 of human PDCD6 (NP_037364.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cell Cycle, Neuroscience, Signal Transduction

Purification

Affinity purification

Positive Control

BT-474

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=22-404

Calculated Molecular Weight

Observed: 16kDa

Fragment

IgG

Symbol

PDCD6

Positive Control 2

HeLa

Positive Control 3

SW620

Positive Control 4

HepG2

Positive Control 5

Mouse liver

Positive Control 6

Mouse kidney

NCBI Official Name

Programmed cell death protein 6

NCBI Organism

Homo sapiens

Other Product Names

Programmed cell death protein 6, Apoptosis-linked gene 2 protein, Probable calcium-binding protein ALG-2, PDCD6, ALG2

Tested Applications

WB, IHC, IF, IP

Physical Properties

Liquid

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