NHLRC1 Antibody

Product Specifications

Background

The protein encoded by this gene is a single subunit E3 ubiquitin ligase. Laforin is polyubiquitinated by the encoded protein. Defects in this intronless gene lead to an accumulation of laforin and onset of Lafora disease, also known as progressive myoclonic epilepsy type 2 (EPM2) .

NCBI Gene ID

378884

Swiss Prot

Q6VVB1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human NHLRC1 (NP_940988.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

Affinity purification

Positive Control

Mouse liver

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 42kDa

Fragment

IgG

Symbol

NHLRC1

Positive Control 2

Mouse brain

Positive Control 3

Mouse heart

Positive Control 4

Rat brain

Positive Control 5

Rat heart

Positive Control 6

Rat liver

NCBI Official Name

NHL repeat containing E3 ubiquitin protein ligase 1

NCBI Organism

Homo sapiens

Other Product Names

EPM2A, EPM2B, MALIN, bA204B7.2, E3 ubiquitin-protein ligase NHLRC1, NHL repeat containing 1, NHL repeat-containing protein 1, RING-type E3 ubiquitin transferase NHLRC1