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NEK3 Antibody

Product Specifications

Background

This gene encodes a member of the NimA (never in mitosis A) family of serine/threonine protein kinases. The encoded protein differs from other NimA family members in that it is not cell cycle regulated and is found primarily in the cytoplasm. The kinase is activated by prolactin stimulation, leading to phosphorylation of VAV2 guanine nucleotide exchange factor, paxillin, and activation of the RAC1 GTPase. Multiple transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

4752

Swiss Prot

P51956

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 267-506 of human NEK3 (NP_689933.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Signal Transduction

Purification

Affinity purification

Positive Control

MCF7

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 55kDa

Fragment

IgG

Symbol

NEK3

Positive Control 2

HL-60

Positive Control 3

THP-1

Positive Control 4

HepG2

Positive Control 5

HeLa

Positive Control 6

Mouse kidney

NCBI Official Name

NIMA-related kinase 3

NCBI Organism

Homo sapiens

Other Product Names

NEK3, HSPK36, MGC29949

Tested Applications

WB, IF

Physical Properties

Liquid

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