NEK3 Antibody
Product Specifications
Background
This gene encodes a member of the NimA (never in mitosis A) family of serine/threonine protein kinases. The encoded protein differs from other NimA family members in that it is not cell cycle regulated and is found primarily in the cytoplasm. The kinase is activated by prolactin stimulation, leading to phosphorylation of VAV2 guanine nucleotide exchange factor, paxillin, and activation of the RAC1 GTPase. Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
4752
Swiss Prot
P51956
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 267-506 of human NEK3 (NP_689933.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
MCF7
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 55kDa
Fragment
IgG
Symbol
NEK3
Positive Control 2
HL-60
Positive Control 3
THP-1
Positive Control 4
HepG2
Positive Control 5
HeLa
Positive Control 6
Mouse kidney
NCBI Official Name
NIMA-related kinase 3
NCBI Organism
Homo sapiens
Other Product Names
NEK3, HSPK36, MGC29949
Tested Applications
WB, IF
Physical Properties
Liquid
Curated Selection
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