LRAT Antibody
Product Specifications
Background
The protein encoded by this gene localizes to the endoplasmic reticulum, where it catalyzes the esterification of all-trans-retinol into all-trans-retinyl ester. This reaction is an important step in vitamin A metabolism in the visual system. Mutations in this gene have been associated with early-onset severe retinal dystrophy and Leber congenital amaurosis 14. Alternative splicing results in multiple transcript variants.
NCBI Gene ID
9227
Swiss Prot
O95237
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-194 of human LRAT (NP_004735.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
Rat testis
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 24kDa
Fragment
IgG
Symbol
LRAT
NCBI Official Name
Lecithin retinol acyltransferase
NCBI Organism
Homo sapiens
Other Product Names
LCA14, lecithin retinol acyltransferase, lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
Tested Applications
WB, IF
Physical Properties
Liquid
Curated Selection
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