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KYNU Antibody

Product Specifications

Background

Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Alternative splicing results in multiple transcript variants.

NCBI Gene ID

8942

Swiss Prot

Q16719

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-307 of human KYNU (NP_001028170.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

Affinity purification

Positive Control

A-549

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 52kDa

Fragment

IgG

Symbol

KYNU

Positive Control 2

THP-1

Positive Control 3

NCI-H460

Positive Control 4

HepG2

Positive Control 5

Mouse spleen

NCBI Official Name

Kynureninase

NCBI Organism

Homo sapiens

Other Product Names

KYNU

Tested Applications

WB, IHC, IF

Physical Properties

Liquid

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