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IL11RA Antibody

Product Specifications

Background

Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Multiple alternatively spliced transcript variants have been found for this gene.

NCBI Gene ID

3590

Swiss Prot

Q14626

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 30-290 of human IL11RA (NP_001136256.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Chemokines & Cytokines, Immunology, Innate Immunity, Stem Cell

Purification

Affinity purification

Positive Control

Mouse kidney

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 45kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

IL11RA

Positive Control 2

Mouse heart

Positive Control 3

Mouse skeletal muscle

Positive Control 4

Rat liver

NCBI Official Name

Interleukin 11 receptor, alpha

NCBI Organism

Homo sapiens

Other Product Names

IL11RA, MGC2146, CRSDA

Tested Applications

WB

Physical Properties

Liquid

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