Histone H2A.Z Antibody
Product Specifications
Background
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality.
NCBI Gene ID
3015
Swiss Prot
P0C0S5
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-128 of human H2AFZ (NP_002097.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
HL-60
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 15kDa
Fragment
IgG
Symbol
H2AFZ
Positive Control 2
MCF7
Positive Control 3
22Rv1
Positive Control 4
PC-12
Positive Control 5
HepG2
Positive Control 6
Mouse testis
NCBI Official Name
Histone H2A.Z
NCBI Organism
Homo sapiens
Other Product Names
Histone H2AZ, H2A/z, H2AFZ, H2AZ
Tested Applications
WB, IHC
Physical Properties
Liquid
Frequently Asked Questions
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